Impact of lifestyle modification practices and pharmacogenetics of ACE I/D gene polymorphism in grade 1 hypertensive patients

Farhana Rahman, Suguna Elumalai, Shanmugapriya Arumugam, Ashni Bhandari, Krishna Prasanth, Nagasundaram Muthiah, Govindasamy Kumaramanickavel · 2025

Read Impact of lifestyle modification practices and pharmacogenetics of ACE I/D gene polymorphism in grade 1 hypertensive patients by Farhana Rahman, Suguna Elumalai, Shanmugapriya Arumugam, Ashni Bhandari, Krishna Prasanth, Nagasundaram Muthiah, Govindasamy Kumaramanickavel (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12704947.txt.

Description

Farhana Rahman and co-authors study blood pressure control and genes in this 2025 paper. Grade 1 hypertension is the mildest stage of high blood pressure. The team asked how lifestyle habits and one gene variant shape control of the condition. They recruited 447 patients who had taken pressure drugs for over a year.

Patients who kept up lifestyle changes had better pressure control. A variant in the ACE gene linked significantly with having hypertension at all. Drug response also split by gene form: one common drug worked best in one group, another drug in the other. The authors back pairing healthy habits with gene-matched drug choice.

Catalog record

CREATORFarhana Rahman, Suguna Elumalai, Shanmugapriya Arumugam, Ashni Bhandari, Krishna Prasanth, Nagasundaram Muthiah, Govindasamy Kumaramanickavel
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE27 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12704947

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