Impact of SARS-Cov-2 exposure during pregnancy on child neurodevelopment: systematic review and meta-analysis

Paloma Alves Miquilussi, Thalis Vasconcellos de Aguiar, Paula Lima da Cruz, Ana Paula Duca, Marcos Ribeiro, Cristiano Miranda de Araújo, Rosane Sampaio Santos, Angela Graciela Deliga Schroder, Ana Chrystina de Souza Crippa · 2025

Read Impact of SARS-Cov-2 exposure during pregnancy on child neurodevelopment: systematic review and meta-analysis by Paloma Alves Miquilussi, Thalis Vasconcellos de Aguiar, Paula Lima da Cruz, Ana Paula Duca, Marcos Ribeiro, Cristiano Miranda de Araújo, Rosane Sampaio Santos, Angela Graciela Deliga Schroder, Ana Chrystina de Souza Crippa (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12704932.txt.

Description

Paloma Alves Miquilussi and co-authors pooled the evidence on whether catching COVID-19 while pregnant affects a baby's brain development, in a 2025 review. Parents and doctors worried that the virus might harm the womb environment. The team searched five databases plus gray sources for studies of children up to age two. They graded study quality with a standard checklist and merged the numbers with care for wide variation.

Nine studies fed the summary and eight fed the pooled math. Overall, exposed and unexposed children showed no clear gap in development. One domain stood apart: fine motor skills, like small hand movements, where exposed children faced more than twice the risk of delay. The authors stress the proof is thin and methods varied, so the signal needs checking in bigger, cleaner studies.

Catalog record

CREATORPaloma Alves Miquilussi, Thalis Vasconcellos de Aguiar, Paula Lima da Cruz, Ana Paula Duca, Marcos Ribeiro, Cristiano Miranda de Araújo, Rosane Sampaio Santos, Angela Graciela Deliga Schroder, Ana Chrystina de Souza Crippa
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE27 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12704932

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