Propagation dynamics of Anaplasma marginale in a Brazilian tick cell line (RBME-6) derived from Rhipicephalus microplus
Gustavo Seron Sanches, Ana Carolina Castro-Santiago, Ricardo Bassini-Silva, Ana Cláudia Calchi, Simone Michaela Simons, Luís Antonio Mathias, Pablo Henrique Nunes, Rosangela Zacarias Machado, Marcos Rogério André, Darci Moraes Barros-Battesti · 2025
Read Propagation dynamics of Anaplasma marginale in a Brazilian tick cell line (RBME-6) derived from Rhipicephalus microplus by Gustavo Seron Sanches, Ana Carolina Castro-Santiago, Ricardo Bassini-Silva, Ana Cláudia Calchi, Simone Michaela Simons, Luís Antonio Mathias, Pablo Henrique Nunes, Rosangela Zacarias Machado, Marcos Rogério André, Darci Moraes Barros-Battesti (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12704782.txt.
Description
Gustavo Seron Sanches and co-authors chart how a cattle disease bacterium grows inside a tick cell line from Brazil. The bacterium, Anaplasma marginale, lives inside red blood cells and causes bovine anaplasmosis, a costly livestock disease worldwide. Growth inside tick cells was well studied in other lines, but its time course was not, as their 2025 study notes.
Cells were infected with bacterium bodies taken from cow blood, and gene copy counts tracked the growth curve. A lag phase came first, then a fast growth phase, then a die off. Survivors settled into a long still phase from day 13 to day 29 after infection. Light microscopy watched the infection in parallel.
Catalog record
| CREATOR | Gustavo Seron Sanches, Ana Carolina Castro-Santiago, Ricardo Bassini-Silva, Ana Cláudia Calchi, Simone Michaela Simons, Luís Antonio Mathias, Pablo Henrique Nunes, Rosangela Zacarias Machado, Marcos Rogério André, Darci Moraes Barros-Battesti |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 32 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |