MoS2-x/C Nanosheets for Antifungal and Anti-Inflammatory Therapy of Aspergillus fumigatus Keratitis in Mice
Zhuhui Feng, Jing Lin, Qian Wang, Lina Zhang, Lingwen Gu, Bing Yu, Xueyun Fu, Daohao Li, Guiqiu Zhao, Cui Li · 2025
Read MoS2-x/C Nanosheets for Antifungal and Anti-Inflammatory Therapy of Aspergillus fumigatus Keratitis in Mice by Zhuhui Feng, Jing Lin, Qian Wang, Lina Zhang, Lingwen Gu, Bing Yu, Xueyun Fu, Daohao Li, Guiqiu Zhao, Cui Li (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12704514.txt.
Description
Zhuhui Feng and co-authors tested ultra-thin sheets of a mineral compound as a treatment for fungal eye infection in mice, in a 2025 study. The infection attacks the clear front of the eye and can scar it badly. Sheets of the compound, mixed with carbon, were first checked in lab dishes against the fungus. Safety was checked in cells and with a standard eye irritation test in live animals.
In dishes, the sheets slowed fungal growth, blocked film growth, and showed good fit with living cells. In mice, treated eyes carried far fewer fungi than untreated ones. Damage to the eye surface was lighter, and levels of two swelling signals fell. Cell tests in human eye cells showed the same drop in those signals. The authors see the sheets as a two-way therapy, killing fungus while calming the swelling that harms sight.
Catalog record
| CREATOR | Zhuhui Feng, Jing Lin, Qian Wang, Lina Zhang, Lingwen Gu, Bing Yu, Xueyun Fu, Daohao Li, Guiqiu Zhao, Cui Li |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 37 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |