Impact of learning APOE genotype on cognitively unimpaired adults: a pre-screening cohort study of the Alzheimer’s Prevention Initiative Generation Study 1

Jessica B Langbaum, Angela R Bradbury, Brian L Egleston, Elisabeth McCarty Wood, Carolyn M Langlois, Emily A Largent, Kristin Harkins, Claire M Erickson, Shana D Stites, Emma Oyen, Marie-Emmanuelle Riviere, Fonda Liu, Ana Graf, Scott Y H Kim, Joshua D Grill, Eric M Reiman, Pierre N Tariot, J Scott R · 2025

Read Impact of learning APOE genotype on cognitively unimpaired adults: a pre-screening cohort study of the Alzheimer’s Prevention Initiative Generation Study 1 by Jessica B Langbaum, Angela R Bradbury, Brian L Egleston, Elisabeth McCarty Wood, Carolyn M Langlois, Emily A Largent, Kristin Harkins, Claire M Erickson, Shana D Stites, Emma Oyen, Marie-Emmanuelle Riviere, Fonda Liu, Ana Graf, Scott Y H Kim, Joshua D Grill, Eric M Reiman, Pierre N Tariot, J Scott R (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12703885.txt.

Description

SummaryBackgroundThe apolipoprotein E (APOE) gene is the best established genetic risk factor for Alzheimer’s disease in later life, with the ε4 allele conferring higher risk. APOE disclosure is becoming increasingly common in the clinical care of people with Alzheimer’s disease and in cognitively unimpaired adults.

Catalog record

CREATORJessica B Langbaum, Angela R Bradbury, Brian L Egleston, Elisabeth McCarty Wood, Carolyn M Langlois, Emily A Largent, Kristin Harkins, Claire M Erickson, Shana D Stites, Emma Oyen, Marie-Emmanuelle Riviere, Fonda Liu, Ana Graf, Scott Y H Kim, Joshua D Grill, Eric M Reiman, Pierre N Tariot, J Scott R
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE29 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12703885

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