The Role of the Vaginal Microbiome in Preterm Premature Rupture of Membranes: A Comprehensive Review of Mechanisms and Clinical Implications

Maryam Alikamali, Sakineh Mohammad‐Alizadeh‐Charandabi, Somayeh Ahmadi, Mohammad Yousef Memar, Mahnaz Shahnazi · 2025

Read The Role of the Vaginal Microbiome in Preterm Premature Rupture of Membranes: A Comprehensive Review of Mechanisms and Clinical Implications by Maryam Alikamali, Sakineh Mohammad‐Alizadeh‐Charandabi, Somayeh Ahmadi, Mohammad Yousef Memar, Mahnaz Shahnazi (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12703050.txt.

Description

Maryam Alikamali and four colleagues review how the vaginal germ mix links to early breaking of the waters in pregnancy, in a twenty twenty-five article. This event, called PPROM, affects about four to five percent of pregnancies and is a top cause of early birth. A healthy vaginal mix is ruled by Lactobacillus germs; a shifted mix is suspect. The team searched three databases for studies on the germ mix and this complication.

The gathered proof sketches a chain: harmful germs climb upward and trigger swelling signals. That swelling attacks the fetal membranes in three ways at once: enzymes chew their fibers, cells die on cue, and oxygen stress damages tissue. Standard antibiotics show limits, so the authors discuss newer care ideas.

Catalog record

CREATORMaryam Alikamali, Sakineh Mohammad‐Alizadeh‐Charandabi, Somayeh Ahmadi, Mohammad Yousef Memar, Mahnaz Shahnazi
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE38 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12703050

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