A Critical Role of DC-SIGN+ Tumor-Associated Macrophages in Colorectal Cancer Immune Evasion and Progression via BCL-3-Mediated PD-L1 Expression
Jianfeng Zhang, Yifan Zhao, Xingchao Wang, Chuang Miao, Wangcheng Xu, Chunhua Wan, Baoying Hu, Fei Qian · 2025
Read A Critical Role of DC-SIGN+ Tumor-Associated Macrophages in Colorectal Cancer Immune Evasion and Progression via BCL-3-Mediated PD-L1 Expression by Jianfeng Zhang, Yifan Zhao, Xingchao Wang, Chuang Miao, Wangcheng Xu, Chunhua Wan, Baoying Hu, Fei Qian (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12702786.txt.
Description
Jianfeng Zhang leads a team on immune cells that help bowel cancer hide. Their study from twenty twenty-five deals with tumor linked macrophages. A mark called DC-SIGN varies on these cells in tumors.
Data from a cancer atlas and a local group were checked first. High mark cells went with worse outlook for patients. Stain and flow tests mapped where the mark sits in tissue. Gene reads split high and low mark cells for compare. Tests show the mark lifts a shield protein via a switch. That shield helps the tumor dodge immune attack.
Catalog record
| CREATOR | Jianfeng Zhang, Yifan Zhao, Xingchao Wang, Chuang Miao, Wangcheng Xu, Chunhua Wan, Baoying Hu, Fei Qian |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 41 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |