Sertraline to reduce recidivism in impulsive violent offenders (ReINVEST): a randomised double blind clinical trial
Tony Butler, Emaediong I. Akpanekpo, Lee Knight, Kristy Robledo, David Greenberg, Andrew Ellis, Stephen Allnutt, Kay Wilhelm, Alison Jones, Rodney Scott, Bianca Ton, Luke Grant, Philip Mitchell, Ross Tynan, Jocelyn Jones, Dominic Villa, Duncan Chappell, Carolynn Dixon, Alison Churchill, Val Gebski, · 2025
Read Sertraline to reduce recidivism in impulsive violent offenders (ReINVEST): a randomised double blind clinical trial by Tony Butler, Emaediong I. Akpanekpo, Lee Knight, Kristy Robledo, David Greenberg, Andrew Ellis, Stephen Allnutt, Kay Wilhelm, Alison Jones, Rodney Scott, Bianca Ton, Luke Grant, Philip Mitchell, Ross Tynan, Jocelyn Jones, Dominic Villa, Duncan Chappell, Carolynn Dixon, Alison Churchill, Val Gebski, (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12702300.txt.
Description
Could a common antidepressant keep violent men from offending again? The ReINVEST trial tested that idea head-on in New South Wales, enrolling 630 men with at least two violent convictions and high impulsiveness scores. After a month on sertraline to weed out early dropouts, the men were randomized to a year of the drug or a placebo. Researchers then tracked new violent convictions through the state database. By twelve months only a third were still engaged with the study, but records covered everyone.
The answer was no: about 22.6 percent of the sertraline group and 22.5 percent of the placebo group were convicted of a new violent offence, a statistical dead heat. A side analysis hinted at fewer domestic violence offences, which the authors treat as a lead, not a finding.
Catalog record
| CREATOR | Tony Butler, Emaediong I. Akpanekpo, Lee Knight, Kristy Robledo, David Greenberg, Andrew Ellis, Stephen Allnutt, Kay Wilhelm, Alison Jones, Rodney Scott, Bianca Ton, Luke Grant, Philip Mitchell, Ross Tynan, Jocelyn Jones, Dominic Villa, Duncan Chappell, Carolynn Dixon, Alison Churchill, Val Gebski, |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 59 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |