Treating RBM20-related cardiomyopathy—Ready for prime time?
Johanna Kohn, Anna-Maria Lauerer, Philipp Hegner, Simon Lebek · 2025
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Description
erious variant that causes severe dilated cardiomyopathy (DCM). After treating human induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs), the authors observed a restoration of downstream molecular defects.2 These findings represent convincing evidence that PE can effectively correct pathogenic mutations associated with cardiovascular diseases.
Catalog record
| CREATOR | Johanna Kohn, Anna-Maria Lauerer, Philipp Hegner, Simon Lebek |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 9 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |