Use of pimobendan in cats: a practical evidence-based review
Sonya G Gordon, Ashley B Saunders, Sonya Wesselowski, Elizabeth L Malcolm, Alice Watson · 2025
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Description
Sonya Gordon and co-authors review the evidence for using a heart drug, pimobendan, in cats, in a 2025 practical review for veterinarians. Heart muscle diseases are the leading cause of heart failure in cats, yet treatments have been limited to water pills and clot preventers, neither of which strengthens the heart itself. Pimobendan, borrowed from dog and human medicine, both sensitizes the heart to calcium and blocks an enzyme.
The review finds potential benefits across feline heart diseases: better pumping and filling, smaller left atria, improved atrial function, and less platelet clumping. A standard dose is generally well tolerated, with stomach upset the commonest side effect. An oral solution is now approved for animals in several regions, though the drug remains unlicensed for cats. It must not be used when outflow from the heart is physically blocked. Case examples ground the recommendations for primary care practice.
Catalog record
| CREATOR | Sonya G Gordon, Ashley B Saunders, Sonya Wesselowski, Elizabeth L Malcolm, Alice Watson |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 31 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |