Novel zoonotic cases of Plasmodium simium from São Paulo with a reference genome of the Brazilian strain
Emilia Manko, Nina Billows, Matthew Higgins, Daniel Ward, Amy Ibrahim, Susana Campino, Silvia Maria Di Santi, Taane G Clark · 2025
Read Novel zoonotic cases of Plasmodium simium from São Paulo with a reference genome of the Brazilian strain by Emilia Manko, Nina Billows, Matthew Higgins, Daniel Ward, Amy Ibrahim, Susana Campino, Silvia Maria Di Santi, Taane G Clark (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12700903.txt.
Description
Emilia Manko and co-authors report human malaria cases from a monkey parasite in Brazil in a 2025 study. The parasite, Plasmodium simium, spills from primates into people and can hide from control work. Sound genome data were lacking, so the team built a reference genome for the Brazilian strain.
They paired two sequencing methods to yield a high grade genome of the strain found near São Paulo. Checks against its close kin, Plasmodium vivax, confirmed known gaps in invasion genes and shifts in surface genes. A scan of 38 samples from Brazil then traced variety and signs of host adaptation, which can sharpen diagnosis and control.
Catalog record
| CREATOR | Emilia Manko, Nina Billows, Matthew Higgins, Daniel Ward, Amy Ibrahim, Susana Campino, Silvia Maria Di Santi, Taane G Clark |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 47 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |