Three-dimensional forward-scattering imaging flow cytometry system for single-cell analysis
Minhong Zhou, Jingjing Zhao, Xinyu Chen, Zunming Zhang, Zhaoyu Lai, Ziqi Zhou, Adam de la Zerda, Yu-Hwa Lo · 2025
Read Three-dimensional forward-scattering imaging flow cytometry system for single-cell analysis by Minhong Zhou, Jingjing Zhao, Xinyu Chen, Zunming Zhang, Zhaoyu Lai, Ziqi Zhou, Adam de la Zerda, Yu-Hwa Lo (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12700570.txt.
Description
Minhong Zhou and co-authors present a new system in 2025 for imaging single cells in three dimensions as they flow past a sensor. The system uses forward scattering, which can show fine detail inside cells without labels.
Strong light that passes straight through has made this kind of imaging hard. The new system uses a needle-like beam of light, a row of tiny mirrors, and math steps to clean the signal. Tests with small structures, gel beads, and human cells showed clear detail at about four hundred cells per second. The setup could later pair with sorting and smart sorting tools.
Catalog record
| CREATOR | Minhong Zhou, Jingjing Zhao, Xinyu Chen, Zunming Zhang, Zhaoyu Lai, Ziqi Zhou, Adam de la Zerda, Yu-Hwa Lo |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 22 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |