Central nervous system infection by Angiostrongylus cantonensis in children: experience from Guangdong, China

Haixia Zhu, Wenlin Wu, Yanping Ran, Jiahao Cai, Wenxiao Wu, Yuan Zhao, Yiru Zeng, Chi Hou, Yang Tian, Huiling Shen, Yani Zhang, Bingwei Peng, Kelu Zheng, Yuanyuan Gao, Xiaojing Li · 2025

Read Central nervous system infection by Angiostrongylus cantonensis in children: experience from Guangdong, China by Haixia Zhu, Wenlin Wu, Yanping Ran, Jiahao Cai, Wenxiao Wu, Yuan Zhao, Yiru Zeng, Chi Hou, Yang Tian, Huiling Shen, Yani Zhang, Bingwei Peng, Kelu Zheng, Yuanyuan Gao, Xiaojing Li (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12699873.txt.

Description

Haixia Zhu and co-authors describe brain and spinal infections from a rat-borne parasite in children, in a 2025 paper. Angiostrongylus cantonensis, the rat lungworm, rarely invades the central nervous system, but cases are rising and children are easily missed. The team reviewed cases at a national neurology center in Guangdong from 2017 to 2024.

Twenty-two children were treated, most under two years old, and about two thirds fell ill between June and October. Fever led the symptoms, then drowsiness and vomiting; notably, none had neck stiffness. Every child showed raised eosinophils in blood, and spinal fluid carried the same signature. Gene sequencing of spinal fluid helped confirm cases. The series sharpens recognition of a sneaky infection.

Catalog record

CREATORHaixia Zhu, Wenlin Wu, Yanping Ran, Jiahao Cai, Wenxiao Wu, Yuan Zhao, Yiru Zeng, Chi Hou, Yang Tian, Huiling Shen, Yani Zhang, Bingwei Peng, Kelu Zheng, Yuanyuan Gao, Xiaojing Li
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE45 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12699873

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