Study protocol for optimising antipsychotic prescribing among hospitalised patients in the acute care setting in Scotland: a national retrospective cohort study
Cosmika Goswami, Tanja Mueller, Alexa Wall, Chris F Johnson, David Grosset, Marion Bennie, Amanj Kurdi · 2025
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Description
Cosmika Goswami and six co-authors lay out a national study of high-dose antipsychotic prescribing in Scottish hospitals, in a 2025 protocol paper. Strong doses of these drugs suit only severe, treatment-resistant illness, and they raise the risk of side effects. Doctors outside mental health may not notice when a dose passes the recommended ceiling, so extra monitoring gets missed. The study aims to map current practice and link dosing to patient outcomes.
The team will use Scotland's electronic prescribing records from 2019 to 2023, linked with hospital and primary care data. Patients on doses above the formulary maximum form the exposed group; the rest are the comparison. Machine learning will help test how high doses relate to outcomes. The findings will shape a decision support tool meant to flag risky prescriptions at the point of care.
Catalog record
| CREATOR | Cosmika Goswami, Tanja Mueller, Alexa Wall, Chris F Johnson, David Grosset, Marion Bennie, Amanj Kurdi |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 35 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |