A case of celiac disease carrying the half DQ2 variant with a variety of psychiatric manifestations
Akiko Sato, Yasuto Kunii, Takuya Tsunoda, Yoshiko Yamaguchi, Koichi Osonoe, Shuzo Hoshino · 2025
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Description
Akiko Sato and colleagues reported a single case in 2025. Their patient was a teenage girl in Japan. She had shown behavior problems since elementary school. Theft and rule breaking were long-standing concerns. Doctors had diagnosed ADHD and conduct problems. Standard psychiatric treatment helped her very little. She also had chronic gut complaints and odd labs. Those physical clues prompted deeper medical testing. A bowel biopsy confirmed celiac disease at last.
Celiac disease is triggered by eating gluten. It is underdiagnosed in Japan and across Asia. The girl also carried a partial genetic risk variant. A gluten-free diet began after diagnosis. Her mental and physical symptoms improved markedly afterward. No relapse appeared during follow-up care. The case warns against purely psychiatric explanations. Gut disease can hide behind behavior problems.
Catalog record
| CREATOR | Akiko Sato, Yasuto Kunii, Takuya Tsunoda, Yoshiko Yamaguchi, Koichi Osonoe, Shuzo Hoshino |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 17 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |