Inhibition of adipocyte lipolysis by vaspin impairs thermoregulation in vivo
Inka Rapöhn, Helen Broghammer, Anne Hoffmann, Kevin Möhlis, Anna Moormann, Isabell Kaczmarek, Doreen Thor, Henning Großkopf, Laura Krieg, Isabel Karkossa, Kristin Schubert, Martin von Bergen, Kerstin Krause, Jana Breitfeld, Peter Kovacs, Nora Klöting, Rima Nuwayhid, Stefan Langer, Adhideb Ghosh, Chr · 2025
Read Inhibition of adipocyte lipolysis by vaspin impairs thermoregulation in vivo by Inka Rapöhn, Helen Broghammer, Anne Hoffmann, Kevin Möhlis, Anna Moormann, Isabell Kaczmarek, Doreen Thor, Henning Großkopf, Laura Krieg, Isabel Karkossa, Kristin Schubert, Martin von Bergen, Kerstin Krause, Jana Breitfeld, Peter Kovacs, Nora Klöting, Rima Nuwayhid, Stefan Langer, Adhideb Ghosh, Chr (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12698850.txt.
Description
Inka Rapöhn and co-authors name a fat-born signal that brakes heat burn in brown fat and so chills the body. Brown fat burns fuel for heat, and its pace ties to weight, sugar, and heart ills. A few spilled signals from fat rule that pace. Their 2025 study finds one, vaspin, spills from brown fat and damps the goad that frees fuel there.
Mice bred to spill extra vaspin in fat cool fast in cold and fast states. The brake works by grip on fat doors that mute the goad path and slow fat burn. Human fat reads and cell tests back the brake in folks too. A tuned brake could guard the body's store in lean times. The find casts fat as its own heat gov.
Catalog record
| CREATOR | Inka Rapöhn, Helen Broghammer, Anne Hoffmann, Kevin Möhlis, Anna Moormann, Isabell Kaczmarek, Doreen Thor, Henning Großkopf, Laura Krieg, Isabel Karkossa, Kristin Schubert, Martin von Bergen, Kerstin Krause, Jana Breitfeld, Peter Kovacs, Nora Klöting, Rima Nuwayhid, Stefan Langer, Adhideb Ghosh, Chr |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 70 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |