Viral Distribution of Wild Boar Exposed to Low (Vaccine Candidate) and High Virulence African Swine Fever Virus Isolates: Immunohistochemical Characterization
Néstor Porras, Antonio Rodríguez-Bertos, Sandra Barroso-Arévalo, Aleksandra Kosowska, Marta Díaz de Frutos, Javier M. De Pablo-Moreno, Mónica Sánchez-Segovia, Jose Ángel Barasona · 2025
Read Viral Distribution of Wild Boar Exposed to Low (Vaccine Candidate) and High Virulence African Swine Fever Virus Isolates: Immunohistochemical Characterization by Néstor Porras, Antonio Rodríguez-Bertos, Sandra Barroso-Arévalo, Aleksandra Kosowska, Marta Díaz de Frutos, Javier M. De Pablo-Moreno, Mónica Sánchez-Segovia, Jose Ángel Barasona (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12697812.txt.
Description
Porras and colleagues map in twenty twenty-five where African swine fever virus sits in wild boar tissues after mild vaccine-strain or fierce wild-strain exposure. Vaccines are a hoped-for long-term control, but judging their safety needs tissue-level evidence. Groups of boar got the fierce strain alone, the mild strain by mouth, or the mild strain then a fierce challenge, in single or repeated doses.
Fierce-strain boar showed bleeding, tissue damage, and virus spread everywhere. Mild-strain boar showed almost no virus beyond the mouth entry tissues. Single-dose vaccinees held the challenge mostly at entry points, while repeat-dose boar showed no virus staining at all. The authors say tissue checks sharpen vaccine safety judgement.
Catalog record
| CREATOR | Néstor Porras, Antonio Rodríguez-Bertos, Sandra Barroso-Arévalo, Aleksandra Kosowska, Marta Díaz de Frutos, Javier M. De Pablo-Moreno, Mónica Sánchez-Segovia, Jose Ángel Barasona |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 65 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |