Protective effects of mango peel extract on carboplatin/5-fluorouracil-induced parotid gland injury and hematopoietic toxicity in male Wistar albino rats: a preclinical study
Raneem F Obeid, Yara Y Mouselhy, Sally A Abdel-halim, Mona Eltaher, Radwa T El-sharkawy · 2025
Read Protective effects of mango peel extract on carboplatin/5-fluorouracil-induced parotid gland injury and hematopoietic toxicity in male Wistar albino rats: a preclinical study by Raneem F Obeid, Yara Y Mouselhy, Sally A Abdel-halim, Mona Eltaher, Radwa T El-sharkawy (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12696213.txt.
Description
Drugs used against head and neck cancers can harm healthy tissue, including the glands that make saliva and the cells that build blood. Raneem Obeid and four co-authors tested in 2025 whether mango peel extract could shield those tissues in rats. Sixty male rats were split into groups that got the drugs alone, the extract alone, both, or neither, over three weeks.
Rats on both kept more weight than rats on the drugs alone, and their blood cell counts fell less. Under the microscope their saliva glands showed less scarring and milder cell damage. The extract did not undo the drugs' drop in blood sugar. The authors read the results as early support for the extract as a helper treatment.
Catalog record
| CREATOR | Raneem F Obeid, Yara Y Mouselhy, Sally A Abdel-halim, Mona Eltaher, Radwa T El-sharkawy |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 43 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |