Longitudinal tracking of neuronal activity from the same cells in the developing brain using Track2p
Jure Majnik, Manon Mantez, Sofia Zangila, Stéphane Bugeon, Léo Guignard, Jean-Claude Platel, Rosa Cossart, Leopoldo Petreanu, Jure Majnik, Manon Mantez, Sofia Zangila, Stéphane Bugeon, Léo Guignard, Jean-Claude Platel, Rosa Cossart · 2025
Read Longitudinal tracking of neuronal activity from the same cells in the developing brain using Track2p by Jure Majnik, Manon Mantez, Sofia Zangila, Stéphane Bugeon, Léo Guignard, Jean-Claude Platel, Rosa Cossart, Leopoldo Petreanu, Jure Majnik, Manon Mantez, Sofia Zangila, Stéphane Bugeon, Léo Guignard, Jean-Claude Platel, Rosa Cossart (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12695024.txt.
Description
Watching the same neurons fire across days is the only way to see a brain circuit grow up, but matching cells between imaging sessions is painstaking. Jure Majnik and co-authors present Track2p, a tracking method based on registering images session by session. They validated it on calcium imaging from the whisker cortex of mouse pups across the first postnatal week, following several hundred individual neurons.
The tracking held up over the full week, letting the team measure how each neuron's activity and stability evolved. One clear transition emerged: activity statistics shifted as arousal states began to shape the cortex. Beyond that finding, the authors offer Track2p as a general tool for developmental studies, including work on how circuits deviate in neurodevelopmental disorders.
Catalog record
| CREATOR | Jure Majnik, Manon Mantez, Sofia Zangila, Stéphane Bugeon, Léo Guignard, Jean-Claude Platel, Rosa Cossart, Leopoldo Petreanu, Jure Majnik, Manon Mantez, Sofia Zangila, Stéphane Bugeon, Léo Guignard, Jean-Claude Platel, Rosa Cossart |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 111 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |