Cell-Free DNA Levels During the First Hours After Liver Transplantation: A Key Biomarker for Patient Survival and Outcomes

Hada C Macher, José L Rubio-Prieto, Noelia García-Fernández, Patrocinio Molinero, Miguel A Gómez-Bravo, Juan M Guerrero, Gonzalo Suárez-Artacho, Amalia Rubio, Karn Wijarnpreecha · 2025

Read Cell-Free DNA Levels During the First Hours After Liver Transplantation: A Key Biomarker for Patient Survival and Outcomes by Hada C Macher, José L Rubio-Prieto, Noelia García-Fernández, Patrocinio Molinero, Miguel A Gómez-Bravo, Juan M Guerrero, Gonzalo Suárez-Artacho, Amalia Rubio, Karn Wijarnpreecha (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12693361.txt.

Description

Hada Macher and co-authors published this study in 2025. It tests whether loose DNA floating in the blood can flag trouble after a liver transplant. This cell-free DNA spills from injured tissue, so its level may reflect how well the new liver survived the move.

The team measured the DNA in 115 transplant patients, starting during surgery and through the first month. Patients whose levels ran high in the first hours went on to suffer more liver damage and complications. They also stayed longer in intensive care and died more often. Long storage times for the donated organ, both cold and warm, went with higher early levels. The authors propose the test as an early warning tool to guide closer care.

Catalog record

CREATORHada C Macher, José L Rubio-Prieto, Noelia García-Fernández, Patrocinio Molinero, Miguel A Gómez-Bravo, Juan M Guerrero, Gonzalo Suárez-Artacho, Amalia Rubio, Karn Wijarnpreecha
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE41 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12693361

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