Human miRNAs in Cancer: Statistical Trends and Cross Kingdom Approach
Maksym Zoziuk, Vittorio Colizzi, Maurizio Mattei, Pavlo Krysenko, Roberta Bernandini, Fabio Massimo Zanzotto, Stefano Marini, Dmitri Koroliouk, Michael T Wolfinger · 2025
Read Human miRNAs in Cancer: Statistical Trends and Cross Kingdom Approach by Maksym Zoziuk, Vittorio Colizzi, Maurizio Mattei, Pavlo Krysenko, Roberta Bernandini, Fabio Massimo Zanzotto, Stefano Marini, Dmitri Koroliouk, Michael T Wolfinger (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12692678.txt.
Description
Maksym Zoziuk and co-authors scan in 2025 the small regulatory RNAs called microRNAs across human cancers, hunting for stable patterns and a cross kingdom twist. These tiny RNAs tune gene activity and often go off track in cancer, but most studies chase one at a time. The team merged proven interaction data with expression data from many cancers, and used a strict cutoff to name the most strongly shifted regulators.
They found sets of microRNAs that were turned down or up again and again across cancers, with matching shifts in their target genes. A sweep of plant microRNAs from many species found some that match the turned down human ones closely in sequence. The patterns give future studies firm leads.
Catalog record
| CREATOR | Maksym Zoziuk, Vittorio Colizzi, Maurizio Mattei, Pavlo Krysenko, Roberta Bernandini, Fabio Massimo Zanzotto, Stefano Marini, Dmitri Koroliouk, Michael T Wolfinger |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 42 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |