Maternal Gestational Diabetes Impairs Fetoplacental Insulin-Induced Vasodilation via AKT/eNOS Pathway and Reduces Placental Efficiency

Clara M Hengst, Maria de Leyre Villar-Ballesteros, Heike Brendel, Sindy Giebe, Coy Brunssen, Alexander Frühauf, Cahit Birdir, Paul D Taylor, Lucilla Poston, Henning Morawietz, Regina Komsa-Penkova · 2025

Read Maternal Gestational Diabetes Impairs Fetoplacental Insulin-Induced Vasodilation via AKT/eNOS Pathway and Reduces Placental Efficiency by Clara M Hengst, Maria de Leyre Villar-Ballesteros, Heike Brendel, Sindy Giebe, Coy Brunssen, Alexander Frühauf, Cahit Birdir, Paul D Taylor, Lucilla Poston, Henning Morawietz, Regina Komsa-Penkova (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12692426.txt.

Description

Gestational Diabetes Mellitus (GDM) increases the long-term risk for metabolic and cardiovascular diseases in the offspring. However, the underlying mechanisms are not well understood. This study investigates the impact of GDM on fetoplacental vascular function and molecular mechanisms underlying endothelial dysfunction. Clinical data and tissue samples were collected from normoglycemic (NG, n = 33) and GDM (n = 19) pregnancies.

Catalog record

CREATORClara M Hengst, Maria de Leyre Villar-Ballesteros, Heike Brendel, Sindy Giebe, Coy Brunssen, Alexander Frühauf, Cahit Birdir, Paul D Taylor, Lucilla Poston, Henning Morawietz, Regina Komsa-Penkova
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE49 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12692426

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