Reply to Abedon, S.T. Dual-Receptor Recognition, Lysis Inhibition, Endolysin Release, and Reaction–Diffusion as Alternative Explanations. Comment on “Rojero et al. Bypassing Evolution of Bacterial Resistance to Phages: The Example of Hyper-Aggressive Phage 0524phi7-1. Int. J. Mol. Sci. 2025, 26, 291
Maria Rojero, Meagan Weaver-Rosen, Philip Serwer · 2025
Read Reply to Abedon, S.T. Dual-Receptor Recognition, Lysis Inhibition, Endolysin Release, and Reaction–Diffusion as Alternative Explanations. Comment on “Rojero et al. Bypassing Evolution of Bacterial Resistance to Phages: The Example of Hyper-Aggressive Phage 0524phi7-1. Int. J. Mol. Sci. 2025, 26, 291 by Maria Rojero, Meagan Weaver-Rosen, Philip Serwer (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12691794.txt.
Description
Maria Rojero, Meagan Weaver-Rosen, and Philip Serwer wrote a reply in two thousand twenty-five to a comment on their phage work. A phage is a virus that infects bacteria, and theirs showed what they call hyper-aggressive behavior. A critic had offered other explanations for what they saw, such as dual-receptor recognition and lysis inhibition.
In the reply, they stress points they say set their phage apart. The cleared zones it forms are lopsided, and far larger than its round plaques on the same plate. It also destroys mature host colonies, unlike other aggressive phages they cite. They argue the zone shape implies movement that needs energy, not simple spreading. Their idea of phage swimming stays, in their words, a viable hypothesis.
Catalog record
| CREATOR | Maria Rojero, Meagan Weaver-Rosen, Philip Serwer |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 22 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |