Psychedelics in Multiple Sclerosis: Mechanisms, Challenges, and Prospects for Neuroimmune Modulation and Repair
Ivan Anchesi, Maria Francesca Astorino, Ivana Raffaele, Deborah Stefania Donato, Serena Silvestro, Aurelio Minuti, Marco Calabrò, Michele Scuruchi, Giovanni Luca Cipriano, Sujatha Kannan, Elizabeth Winans Tucker · 2025
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Description
Multiple Sclerosis (MS) therapies effectively modulate peripheral immune responses but largely fail to promote neural repair within the central nervous system. This review evaluates whether psychedelic compounds (PSYs), via 5-HT2A activation, can fill a critical therapeutic gap: the need for agents that simultaneously suppress neuroinflammation and promote regeneration.
Catalog record
| CREATOR | Ivan Anchesi, Maria Francesca Astorino, Ivana Raffaele, Deborah Stefania Donato, Serena Silvestro, Aurelio Minuti, Marco Calabrò, Michele Scuruchi, Giovanni Luca Cipriano, Sujatha Kannan, Elizabeth Winans Tucker |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 103 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |