Chronic Ethanol Exposure Induces Early Epithelial-to-Mesenchymal Transition (EMT) and Premalignant Changes in Gingival Keratinocytes: An In Vitro Model of Very Early Oral Carcinogenesis
Martin Philipp Dieterle, Thorsten Steinberg, Ayman Husari, Pascal Tomakidi · 2025
Read Chronic Ethanol Exposure Induces Early Epithelial-to-Mesenchymal Transition (EMT) and Premalignant Changes in Gingival Keratinocytes: An In Vitro Model of Very Early Oral Carcinogenesis by Martin Philipp Dieterle, Thorsten Steinberg, Ayman Husari, Pascal Tomakidi (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12691217.txt.
Description
Highlights What are the main findings? Chronic ethanol exposure of gingival keratinocytes induces biochemical and morphological changes that resemble the very early steps in the development of oral squamous cell carcinoma.Even morphologically “normal” keratinocytes already show early, premalignant metabolic changes, which underscores the concept of a stepwise cell transformation from a benign to a premalignant phenotype.
Catalog record
| CREATOR | Martin Philipp Dieterle, Thorsten Steinberg, Ayman Husari, Pascal Tomakidi |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 79 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |