Periodontopathogens degrade angiotensin I from the human renin–angiotensin system through surface-attached proteases
Irena Waligórska, Krzysztof M Żak, Natalia Mikrut, Joanna Budziaszek, Volodymyr Medviediev, Ewa Bielecka, Tomasz Kantyka, Joanna Kozieł, Ida B Thøgersen, Jan J Enghild, Przemysław Grudnik, Jan Potempa, Mirosław Książek · 2025
Read Periodontopathogens degrade angiotensin I from the human renin–angiotensin system through surface-attached proteases by Irena Waligórska, Krzysztof M Żak, Natalia Mikrut, Joanna Budziaszek, Volodymyr Medviediev, Ewa Bielecka, Tomasz Kantyka, Joanna Kozieł, Ida B Thøgersen, Jan J Enghild, Przemysław Grudnik, Jan Potempa, Mirosław Książek (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12686026.txt.
Description
Irena Waligórska and co-authors show how gum bacteria can cut a hormone signal in this 2025 study. The signal belongs to a body system that controls blood pressure. Its first form can be cut into a form that raises pressure, or into a form with the opposed effect.
Two bacteria that live in the mouth and drive gum disease each carry an enzyme on their surface that makes the second, calmer form. Tests with many methods showed these enzymes are the ones that break down the first form in both bacteria. Crystal views explain the odd cutting style of one of them. Removing the enzyme cut the harm of one bacterium in a moth larva model.
Catalog record
| CREATOR | Irena Waligórska, Krzysztof M Żak, Natalia Mikrut, Joanna Budziaszek, Volodymyr Medviediev, Ewa Bielecka, Tomasz Kantyka, Joanna Kozieł, Ida B Thøgersen, Jan J Enghild, Przemysław Grudnik, Jan Potempa, Mirosław Książek |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 58 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |