Circulating NET Biomarkers as Predictors of Inflammatory Storm Escalation and Critical Illness in COVID-19

Wenjuan Liu, Xin Pan, Ruyue Fan, Ying Yang, Na Sun, Peibin Hou, Zuowang Cheng, Chuanjun Huang, Shuai Liu, Lili Su · 2025

Read Circulating NET Biomarkers as Predictors of Inflammatory Storm Escalation and Critical Illness in COVID-19 by Wenjuan Liu, Xin Pan, Ruyue Fan, Ying Yang, Na Sun, Peibin Hou, Zuowang Cheng, Chuanjun Huang, Shuai Liu, Lili Su (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12685590.txt.

Description

COVID-19 demonstrates distinct clinical heterogeneity, ranging from mild symptoms to severe acute respiratory distress syndrome (ARDS). Neutrophil extracellular traps (NETs), which are web-like structures consisting of decondensed DNA adorned with cytotoxic proteins such as myeloperoxidase (MPO) and citrullinated histone H3 (CitH3), play a crucial role in pathogen containment. However, they may also promote immunothrombosis and tissue injury.

Catalog record

CREATORWenjuan Liu, Xin Pan, Ruyue Fan, Ying Yang, Na Sun, Peibin Hou, Zuowang Cheng, Chuanjun Huang, Shuai Liu, Lili Su
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE27 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12685590

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