Circulating long non-coding RNAs as predictors of type 2 diabetes mellitus development: results from the CORDIOPREV study
Hatim Boughanem, María José Párraga-Viúdez, Ana Ojeda-Rodríguez, Juan Luis Romero-Cabrera, Eugenia Ruiz-Díaz Narváez, Alejandro López-Moreno, José David Torres-Peña, Manuel Macías-González, Juan Francisco Alcalá-Díaz, Antonio Pablo Arenas-de Larriva, Pablo Pérez-Martínez, Javier Delgado-Lista, José · 2025
Read Circulating long non-coding RNAs as predictors of type 2 diabetes mellitus development: results from the CORDIOPREV study by Hatim Boughanem, María José Párraga-Viúdez, Ana Ojeda-Rodríguez, Juan Luis Romero-Cabrera, Eugenia Ruiz-Díaz Narváez, Alejandro López-Moreno, José David Torres-Peña, Manuel Macías-González, Juan Francisco Alcalá-Díaz, Antonio Pablo Arenas-de Larriva, Pablo Pérez-Martínez, Javier Delgado-Lista, José (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12683892.txt.
Description
Hatim Boughanem and co-authors test, in a 2025 study, whether long non coding RNAs floating in the blood can forecast who will develop type 2 diabetes. Standard tools catch the disease late and miss many future cases. These RNA molecules, which regulate genes without making proteins, have emerged as candidate early markers.
The data come from a Spanish prevention trial cohort. In all, 462 participants without diabetes were followed for five years. They ate either a Mediterranean or a comparison diet under the trial's design. Blood RNA profiles from the start were checked against who developed diabetes. The study also asked whether diet changed the markers' predictive power. A blood test that flags risk years ahead could aim prevention at the right people. The diet angle matters too: a marker that diet can move is also a possible gauge of prevention working.
Catalog record
| CREATOR | Hatim Boughanem, María José Párraga-Viúdez, Ana Ojeda-Rodríguez, Juan Luis Romero-Cabrera, Eugenia Ruiz-Díaz Narváez, Alejandro López-Moreno, José David Torres-Peña, Manuel Macías-González, Juan Francisco Alcalá-Díaz, Antonio Pablo Arenas-de Larriva, Pablo Pérez-Martínez, Javier Delgado-Lista, José |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 40 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |