Cultivar to chemotype: characterizing complex botanicals with mass spectrometry metabolomics
Joshua J. Kellogg, R. Teal Jordan, Madhusha M. Ranaweera, Kelsey Custer, Savannah G. Anez, Julia Bendlin, Francisco T. Chacon, Xiaoling Chen · 2025
Read Cultivar to chemotype: characterizing complex botanicals with mass spectrometry metabolomics by Joshua J. Kellogg, R. Teal Jordan, Madhusha M. Ranaweera, Kelsey Custer, Savannah G. Anez, Julia Bendlin, Francisco T. Chacon, Xiaoling Chen (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC12679226.txt.
Description
Joshua J Kellogg and colleagues review methods for characterizing complex botanical products in a 2025 article. Botanicals include herbal medicines and plant supplements, whose sales and use have climbed for decades. Correct identification matters, since swapped or adulterated material can change safety and effect.
The review focuses on untargeted mass spectrometry metabolomics, a method that profiles thousands of small molecules in a mixture at once. It explains data analysis routes and gives case studies showing the method can classify plant samples by type, detect adulteration, and reveal variation between materials. Challenges for the growing field are also mapped, linking chemistry to nutrition, medicine, and toxicity questions.
Catalog record
| CREATOR | Joshua J. Kellogg, R. Teal Jordan, Madhusha M. Ranaweera, Kelsey Custer, Savannah G. Anez, Julia Bendlin, Francisco T. Chacon, Xiaoling Chen |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 67567 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |