Renal thrombotic microangiopathy impairs renal function recovery in lupus nephritis
Manhuai Zhang, Xinxin Zhang, Wang Xiang, Jianwen Yu, Xin Wang, Hongjian Ye, Zhong Zhong, Ruihan Tang, Xi Xia, Wei Chen · 2025
Read Renal thrombotic microangiopathy impairs renal function recovery in lupus nephritis by Manhuai Zhang, Xinxin Zhang, Wang Xiang, Jianwen Yu, Xin Wang, Hongjian Ye, Zhong Zhong, Ruihan Tang, Xi Xia, Wei Chen (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12676121.txt.
Description
Manhuai Zhang and nine co-authors studied a small-vessel clotting injury in the kidneys of lupus patients, in a study from twenty twenty-five. The injury, called thrombotic microangiopathy, complicates lupus kidney disease and worsens its course. The team drew on a large single-center lupus database spanning over two decades.
About one in twenty biopsy-proven patients showed the injury. After matching like with like, those patients recovered kidney function less often and faced a far higher risk of needing dialysis or transplant. Scarring share in the kidney's filters predicted recovery within the injured group. The authors argue the injury deserves early attention in treatment planning for lupus kidney disease.
Catalog record
| CREATOR | Manhuai Zhang, Xinxin Zhang, Wang Xiang, Jianwen Yu, Xin Wang, Hongjian Ye, Zhong Zhong, Ruihan Tang, Xi Xia, Wei Chen |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 25 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |