Unraveling atherosclerosis through single-cell RNA sequencing: insights into cellular heterogeneity and disease mechanisms
Carlos Vicente Serrano, Matheus Laterza Ribeiro, Luciana Dornfeld Bichuette, Bruna Romanelli Scarpa Matuck, Patricia Severino, Kenneth J. Gollob, João A.C. Lima, Peter Libby · 2025
Read Unraveling atherosclerosis through single-cell RNA sequencing: insights into cellular heterogeneity and disease mechanisms by Carlos Vicente Serrano, Matheus Laterza Ribeiro, Luciana Dornfeld Bichuette, Bruna Romanelli Scarpa Matuck, Patricia Severino, Kenneth J. Gollob, João A.C. Lima, Peter Libby (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12671654.txt.
Description
Carlos Vicente Serrano and co-authors reviewed in 2025 how a new gene-reading tool is changing study of artery plaque. The disease, atherosclerosis, builds fatty, swollen patches in artery walls and is a top cause of death world-wide. Its course is complex and still not fully mapped. Reading the genes of one cell at a time lets teams list each cell type inside a plaque and see what each one does.
The review sums up how that single-cell method works and what it has shown so far. It tracks how the tool traces the start and growth of plaques. It also notes drug targets the method has brought to light. Readers get a short, clear tour of a fast-moving field.
Catalog record
| CREATOR | Carlos Vicente Serrano, Matheus Laterza Ribeiro, Luciana Dornfeld Bichuette, Bruna Romanelli Scarpa Matuck, Patricia Severino, Kenneth J. Gollob, João A.C. Lima, Peter Libby |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 23 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |