Risk Factors, Diagnostic Challenges, and Emerging Therapeutic Strategies for ICU-Acquired Weakness: A Brief Review

Xiaojie Zhang, Zixuan Wang, Jing Wang, Fei Wu, Le Xia, Suqin Shi, Min Zhu, Jinqiang Zhuang · 2025

Read Risk Factors, Diagnostic Challenges, and Emerging Therapeutic Strategies for ICU-Acquired Weakness: A Brief Review by Xiaojie Zhang, Zixuan Wang, Jing Wang, Fei Wu, Le Xia, Suqin Shi, Min Zhu, Jinqiang Zhuang (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12671084.txt.

Description

Surviving intensive care can leave patients too weak to breathe or walk unaided, a complication called ICU-acquired weakness. Xiaojie Zhang and co-authors review its risks, detection, and treatments in a 2025 paper. Diagnosis is the choke point: bedside scales are subjective, while ultrasound and blood biomarkers are promising but not yet routine.

Prevention leads the management list, especially getting patients moving within the first one to three days under a structured care bundle. Nutrition aimed at protein balance, including specific supplements, supports the muscle side. A myostatin-blocking drug has even raised muscle mass in trials. The authors close by demanding sharper early diagnostics, since every later therapy depends on spotting weakness in time.

Catalog record

CREATORXiaojie Zhang, Zixuan Wang, Jing Wang, Fei Wu, Le Xia, Suqin Shi, Min Zhu, Jinqiang Zhuang
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE32 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12671084

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