The YTHDC1-m6A-MEG3 Regulatory Axis in Radiation-Induced Liver Injury: Deciphering Early-Stage Epitranscriptomic Alterations and Molecular Dynamics

Cun-yang Guo, Yi-fei Du, Hui-cong Yan, Fang-qi Tian, Ping Xu · 2025

Read The YTHDC1-m6A-MEG3 Regulatory Axis in Radiation-Induced Liver Injury: Deciphering Early-Stage Epitranscriptomic Alterations and Molecular Dynamics by Cun-yang Guo, Yi-fei Du, Hui-cong Yan, Fang-qi Tian, Ping Xu (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12670009.txt.

Description

A peer-reviewed research article from Europe PMC (2025). Radiation-induced liver injury (RILI) remains one of the most severe complications encountered during radiotherapy for hepatocellular carcinoma (HCC), cholangiocarcinoma, and tumors of the right lower lung. Although clinically significant, the molecular mechanisms that drive RILI are still incompletely understood. In our recent study published in Cell Death and Disease, entitled “The YTHDC1 Reader Protein Recognizes and Regulates the lncRNA MEG3 Following Its METTL3-Mediated m6A Methylation: A Novel Mechanism Early During RILI”, we investigated in depth the epitranscriptomic regulation of RILI pathogenesis.

Catalog record

CREATORCun-yang Guo, Yi-fei Du, Hui-cong Yan, Fang-qi Tian, Ping Xu
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE23 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12670009

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