Design, biological evaluation, solvatochromic, DFT, and molecular docking studies of new metal complexes derived from a semicarbazone ligand

Magdy A Ibrahim, A Taha, Omima M I Adly, Shery A Fahmy, Maged Abdelaziz, Nesma Salah · 2025

Read Design, biological evaluation, solvatochromic, DFT, and molecular docking studies of new metal complexes derived from a semicarbazone ligand by Magdy A Ibrahim, A Taha, Omima M I Adly, Shery A Fahmy, Maged Abdelaziz, Nesma Salah (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12669734.txt.

Description

Magdy Ibrahim and co-authors made new metal compounds in 2025 from a semicarbazone base and tested them for use in tech and in care. The base was paired with nickel, cobalt, and iron ions. A full kit of measures set the shapes of the three as eight-sided forms. Light tests in unlike solvents showed the glow shifts with the bath, and math models backed that the lit state is more polar than the ground state.

The cobalt build showed the strongest light-bending traits, a plus for optical gear. In lab assays the compounds killed germs and cancer cells at note-worthy rates. Docking runs showed firm fits into target proteins. The team pitches the set as a dual-use lead.

Catalog record

CREATORMagdy A Ibrahim, A Taha, Omima M I Adly, Shery A Fahmy, Maged Abdelaziz, Nesma Salah
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE56 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12669734

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