Historical and current spatiotemporal patterns of wild and vaccine-derived poliovirus spread
Darlan da Silva Candido, Simon Dellicour, Laura V. Cooper, Carlos A. Prete, David Jorgensen, Christopher B. Uzzell, Arend Voorman, Hil Lyons, Dimitra Klapsa, Manasi Majumdar, Kafayat Arowolo, Corey M. Peak, Ananda S. Bandyopadhyay, Javier Martin, Nicholas C. Grassly, Isobel M. Blake · 2025
Read Historical and current spatiotemporal patterns of wild and vaccine-derived poliovirus spread by Darlan da Silva Candido, Simon Dellicour, Laura V. Cooper, Carlos A. Prete, David Jorgensen, Christopher B. Uzzell, Arend Voorman, Hil Lyons, Dimitra Klapsa, Manasi Majumdar, Kafayat Arowolo, Corey M. Peak, Ananda S. Bandyopadhyay, Javier Martin, Nicholas C. Grassly, Isobel M. Blake (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12669034.txt.
Description
Darlan da Silva Candido and co-authors chart how poliovirus, wild and vaccine-born, has spread across the map in a 2025 study. Eradication is close, yet vaccine-derived type two outbreaks have become the main threat, and nobody had measured their spread patterns against the wild virus's history.
From 2016 to 2023, over three thousand vaccine-derived cases formed seventy-five outbreaks across thirty-nine countries. A typical outbreak circulated for about two hundred days and reached a few hundred kilometers, with big ones advancing a few kilometers a day. Borders slowed the wavefront when population immunity ran high. Gene-based geography on over fifteen hundred wild virus sequences showed history rhyming: similar speeds, and cross-border spread mostly one-way between neighbors. The authors turn the measurements into guidance for how wide vaccination responses must reach.
Catalog record
| CREATOR | Darlan da Silva Candido, Simon Dellicour, Laura V. Cooper, Carlos A. Prete, David Jorgensen, Christopher B. Uzzell, Arend Voorman, Hil Lyons, Dimitra Klapsa, Manasi Majumdar, Kafayat Arowolo, Corey M. Peak, Ananda S. Bandyopadhyay, Javier Martin, Nicholas C. Grassly, Isobel M. Blake |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 67 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |