The Predictive Value of Initial Trough Concentration of Voriconazole and Procalcitonin in Hepatotoxic Adverse Events
Lijuan Chen, Xinwen Wang, Xiaoli Wu, Haiyan Qin, Hongchao Zhu · 2025
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Description
PurposeThis study aimed to evaluate the predictive value of initial trough concentration (Cmin) of voriconazole (VCZ) and procalcitonin (PCT) in hepatotoxic adverse events.Patients and MethodsA retrospective analysis was performed on clinical data from 170 patients administered VCZ at our institution between January 2021 and July 2025. Risk factors associated with VCZ-induced hepatotoxicity were identified through binary logistic regression analysis.
Catalog record
| CREATOR | Lijuan Chen, Xinwen Wang, Xiaoli Wu, Haiyan Qin, Hongchao Zhu |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 34 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |