Paroxetine-induced black hairy tongue and necrotizing sialometaplasia: a case report

Zhuang Ying Lee, Manjit Dhillon · 2025

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Description

Zhuang Ying Lee and Manjit Dhillon report two mouth conditions tied to an antidepressant in a 2025 case report. A twenty-seven-year-old British woman developed repeated soft palate ulcers a few months after starting paroxetine for her mental health. The ulcers were treated gently and quieted.

Nineteen months later she returned with an inflamed, ulcerated palate and a brown, hairy-looking tongue covered in debris. Both black hairy tongue and the salivary gland disorder in the title are harmless but alarming, and both share triggers like smoking and certain drugs. Since paroxetine was not helping her mood, doctors switched her medication. Both mouth problems improved markedly once the drug stopped, supporting the link.

Catalog record

CREATORZhuang Ying Lee, Manjit Dhillon
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE10 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12664130

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