Identification of a novel PRUNE2::NTRK2 gene fusion in soft tissue sarcoma patients—friend or foe? Case series
Klaudia Bobak, Andrzej Tysarowski, Katarzyna A. Seliga, Jakub Pia̧tkowski, Paweł Golik, Mateusz J. Spałek, Anna Szumera-Ciećkiewicz, Piotr Rutkowski, Anna M. Czarnecka · 2025
Read Identification of a novel PRUNE2::NTRK2 gene fusion in soft tissue sarcoma patients—friend or foe? Case series by Klaudia Bobak, Andrzej Tysarowski, Katarzyna A. Seliga, Jakub Pia̧tkowski, Paweł Golik, Mateusz J. Spałek, Anna Szumera-Ciećkiewicz, Piotr Rutkowski, Anna M. Czarnecka (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12663043.txt.
Description
Soft tissue sarcomas (STS) are rare mesenchymal tumors in which gene fusions occur in approximately one-third of cases, serving as key diagnostic and therapeutic targets. This study investigates the presence and implications of gene fusions in STS, focusing on a novel PRUNE2::NTRK2 gene fusion identified in two adult patients.
Catalog record
| CREATOR | Klaudia Bobak, Andrzej Tysarowski, Katarzyna A. Seliga, Jakub Pia̧tkowski, Paweł Golik, Mateusz J. Spałek, Anna Szumera-Ciećkiewicz, Piotr Rutkowski, Anna M. Czarnecka |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 30 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |