Trajectory of genome editing technology

Yonglun Luo, Stanislaus Antony Ceasar, Karim Benabdellah · 2025

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Description

Yonglun Luo, Stanislaus Antony Ceasar, and Karim Benabdellah trace three decades of genome editing in this 2025 piece. The field rewrites DNA to change traits, and each new tool has widened what can be edited. The article opens a journal collection on the theme.

Early edits relied on slow, random methods. Zinc finger tools in the mid-nineties gave the first targeted edits, though cost and off-target cuts limited their spread. Later systems, from TALENs to CRISPR, made editing cheaper and sharper. The authors chart publication growth across the tool families. They frame the collection as support for the next wave of editing tools and uses.

Catalog record

CREATORYonglun Luo, Stanislaus Antony Ceasar, Karim Benabdellah
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE10 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12661890

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