The prognostic and clinical utility of circulating tumor DNA in diffuse large B-cell lymphoma: a systematic review and meta-analysis
Shayan Forghani, Amirhossein Shahsavand, Reza Samiee, Mohammadamin Kharaghani, Azadeh Kiumarsi, Fatemeh Mahdavi Sabet, Saba Akbarzadeh, Sajjad Fattahniya, Mohammadreza Rostami, Soroush Rad, Amir Hossein Mirhosseini, Tahereh Rostami, Ghasem Janbabai · 2025
Read The prognostic and clinical utility of circulating tumor DNA in diffuse large B-cell lymphoma: a systematic review and meta-analysis by Shayan Forghani, Amirhossein Shahsavand, Reza Samiee, Mohammadamin Kharaghani, Azadeh Kiumarsi, Fatemeh Mahdavi Sabet, Saba Akbarzadeh, Sajjad Fattahniya, Mohammadreza Rostami, Soroush Rad, Amir Hossein Mirhosseini, Tahereh Rostami, Ghasem Janbabai (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12660778.txt.
Description
Forghani leads a team pooling studies on blood-borne tumor DNA in an aggressive lymphoma in a 2025 review. Circulating tumor DNA offers a needle-light way to track disease burden and change. Dozens of studies linked it to survival.
High starting levels meant higher progression risk. Tumor DNA still present at the end of treatment carried the strongest warning by far. In scan-negative patients, a positive DNA result was highly specific for coming relapse. In scan-positive patients, a negative DNA result cut the relapse risk sharply. The authors say DNA readings refine what scans show. Standardizing test protocols is the main need. DNA-guided management trials come next.
Catalog record
| CREATOR | Shayan Forghani, Amirhossein Shahsavand, Reza Samiee, Mohammadamin Kharaghani, Azadeh Kiumarsi, Fatemeh Mahdavi Sabet, Saba Akbarzadeh, Sajjad Fattahniya, Mohammadreza Rostami, Soroush Rad, Amir Hossein Mirhosseini, Tahereh Rostami, Ghasem Janbabai |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 50 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |