Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy

Musarrat Ijaz, Asadullah Madni, Haji Muhammad Shoaib Khan, Tahreem Arshad, Sidra Meer, Farhat Ijaz, Naveed Akhtar, Modhi O Alotaibi, Areej Turkistani, Gaber El-Saber Batiha · 2025

Read Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy by Musarrat Ijaz, Asadullah Madni, Haji Muhammad Shoaib Khan, Tahreem Arshad, Sidra Meer, Farhat Ijaz, Naveed Akhtar, Modhi O Alotaibi, Areej Turkistani, Gaber El-Saber Batiha (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12660706.txt.

Description

Musarrat Ijaz and co-authors pack two forms of vitamin E into tiny lipid carriers in a gel, aiming at stronger skin anti-aging effects, in a study from 2025. The carriers hold fat-loving ingredients well, release them slowly, and hydrate skin by sealing it. Six versions varied the solid and liquid lipids and the surfactant, plus one placebo.

All versions trapped 66 to 93 percent of the vitamin, with particles from 68 to 290 nanometers. Release came in two phases: a burst, then a slow tail. In skin tests, the gel kept the vitamin in the skin with little passing through. On volunteers, the best gel raised moisture retention up to 68 percent and improved elasticity more than a plain solution gel. The authors credit pairing both vitamin forms in one carrier.

Catalog record

CREATORMusarrat Ijaz, Asadullah Madni, Haji Muhammad Shoaib Khan, Tahreem Arshad, Sidra Meer, Farhat Ijaz, Naveed Akhtar, Modhi O Alotaibi, Areej Turkistani, Gaber El-Saber Batiha
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE69 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12660706

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