Hsa-miR-423-5p selectively loaded in hypoxic exosomes reduces the sensitivity of normoxic hepatocellular carcinoma to sorafenib via autophagy

Bian Shu, Min Zou, Rui Liao, Diguang Wen, Xianzhi Gao, Jiao Lu, Hua Song, Ziyi Sheng, Zuojin Liu, Yu You · 2025

Read Hsa-miR-423-5p selectively loaded in hypoxic exosomes reduces the sensitivity of normoxic hepatocellular carcinoma to sorafenib via autophagy by Bian Shu, Min Zou, Rui Liao, Diguang Wen, Xianzhi Gao, Jiao Lu, Hua Song, Ziyi Sheng, Zuojin Liu, Yu You (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12659515.txt.

Description

A peer-reviewed research article from Europe PMC (2025). BackgroundFor patients with advanced hepatocellular carcinoma, sorafenib is considered a highly effective targeted molecular drug; however, sorafenib resistance limits its therapeutic efficacy. Hepatocellular carcinoma, a type of solid tumour, contains hypoxic and oxygen-rich regions within its internal structure.

Catalog record

CREATORBian Shu, Min Zou, Rui Liao, Diguang Wen, Xianzhi Gao, Jiao Lu, Hua Song, Ziyi Sheng, Zuojin Liu, Yu You
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE52 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12659515

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