CAFs-derived SPI1 in tumor fibroblasts promotes malignant behaviors of liver cancer cells and immune escape by regulating HRAS and PD-L1 transcription
Ke Miao, Jiaren Zhou, Jieyun Chen · 2025
Read CAFs-derived SPI1 in tumor fibroblasts promotes malignant behaviors of liver cancer cells and immune escape by regulating HRAS and PD-L1 transcription by Ke Miao, Jiaren Zhou, Jieyun Chen (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12659378.txt.
Description
BackgroundAs the fifth most common cancer worldwide, hepatocellular carcinoma (HCC) is a highly malignant disease with a formidable prognosis. Within the tumor microenvironment, cancer-associated fibroblasts (CAFs) play a paramount role in tumorigenesis and progression by providing a supportive environment for cancer cells.
Catalog record
| CREATOR | Ke Miao, Jiaren Zhou, Jieyun Chen |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 37 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |