Polyethylene glycol loxenatide reduces NETosis and immunofluorescence hyperactivation in Behçet’s disease
Fang Jia, Xiaoli Wu, Huiyang Sheng · 2025
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Description
BackgroundNeutrophil hyperactivation, particularly through the release of neutrophil extracellular traps (NETosis), plays a crucial role in driving vascular inflammation in Behçet’s disease (BD). While pyroptosis has been linked to the pathogenesis of BD, the effects of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) on neutrophil dysregulation have not been previously explored.
Catalog record
| CREATOR | Fang Jia, Xiaoli Wu, Huiyang Sheng |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 42 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |