Molecular basis of sodium channel inactivation
Yichen Liu, Jason D Galpin, Christopher A Ahern, Francisco Bezanilla · 2025
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Description
Voltage-gated sodium channels initiate action potentials and control electrical signaling throughout the animal kingdom. Fast inactivation is an essential auto-inhibitory mechanism and requisite component of sodium channel physiology. Recent structural and electrophysiological results are inconsistent with the canonical ball and chain model of fast inactivation thus necessitating an updated theoretical framework.
Catalog record
| CREATOR | Yichen Liu, Jason D Galpin, Christopher A Ahern, Francisco Bezanilla |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 52 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |