Epigenetic Clocks: Beyond Biological Age, Using the Past to Predict the Present and Future

Runyu Liang, Qiang Tang, Jia Chen, Luwen Zhu · 2025

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Description

Two people of the same age can be aging at very different speeds, and this 2024 review explains a tool that can tell them apart. Runyu Liang, Qiang Tang, Jia Chen, and Luwen Zhu survey epigenetic clocks, which read chemical marks on DNA to estimate biological age. The marks change in steady patterns across life and across body tissues.

Clocks built from those patterns can flag faster or slower aging and predict risks of death and age-linked disease. That makes them attractive for testing whether a diet, drug, or habit truly slows aging. The authors are clear that real hurdles remain, from cost to consistency across populations. They frame the clocks as powerful but unfinished instruments for the science of aging.

Catalog record

CREATORRunyu Liang, Qiang Tang, Jia Chen, Luwen Zhu
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE84 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12539533

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