Neuroinflammation as a Link in Parkinson’s and Alzheimer’s Diseases: A Systematic Review and Meta-Analysis

Anna Tylutka, Piotr Żabiński, Łukasz Walas, Agnieszka Zembron-Lacny · 2025

Read Neuroinflammation as a Link in Parkinson’s and Alzheimer’s Diseases: A Systematic Review and Meta-Analysis by Anna Tylutka, Piotr Żabiński, Łukasz Walas, Agnieszka Zembron-Lacny (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12539528.txt.

Description

Inflammation inside the brain may be a shared thread between the two most common diseases of the aging brain. Anna Tylutka and co-authors gather the evidence in a 2024 review and meta-analysis on Alzheimer's and Parkinson's diseases. They searched two large databases for studies from 2009 to 2023.

Thirty-seven papers met their rules. Patients with either disease showed higher levels of a signal protein called IL-6 than healthy controls. Alzheimer's patients also ran high on a second signal, while Parkinson's patients ran high on a third tied to inflammation. Results varied a lot between studies, so the authors urge care, but the pattern backs inflammation as a real link worth targeting.

Catalog record

CREATORAnna Tylutka, Piotr Żabiński, Łukasz Walas, Agnieszka Zembron-Lacny
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE43 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12539528

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