Chronic Cerebral Deterioration - A Comprehensive View of Old-Age Cerebral Deterioration

Jan Willem van Dalen · 2025

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Description

Jan Willem van Dalen argues that doctors see brain decline in old age too narrowly in this 2024 paper. The usual view tracks a one-way path from brain changes to memory complaints, mild impairment, and then dementia. Van Dalen points out that many early signs are not about memory at all. Shifts in personality, balance trouble, muscle loss, weight loss, and changed sleep can all come first. Falling blood pressure and cholesterol can also appear early.

He proposes chronic cerebral deterioration as a broader concept that gathers these signs under one frame. On this view, several factors now called dementia risks are really early symptoms of decline already under way. Naming them as such could cut wasted prevention research. It could also help spot the older people most likely to need care.

Catalog record

CREATORJan Willem van Dalen
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE29 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12539498

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