CORRELATION OF TPO ANTIBODY CONCENTRATION WITH THYROID HORMONES AS A PREDICTOR OF CLINICAL HYPOTHYROIDISM
Mila Vasilj-Mihaljević, Ivan Mihaljević, Sanja Bekić, Željko Zubčić, Ana Vasilj, Danijela Daus-Šebeđak, Ivana Škrlec, Jasminka Talapko · 2024
Read CORRELATION OF TPO ANTIBODY CONCENTRATION WITH THYROID HORMONES AS A PREDICTOR OF CLINICAL HYPOTHYROIDISM by Mila Vasilj-Mihaljević, Ivan Mihaljević, Sanja Bekić, Željko Zubčić, Ana Vasilj, Danijela Daus-Šebeđak, Ivana Škrlec, Jasminka Talapko (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12490479.txt.
Description
Mila Vasilj-Mihaljević and seven co-authors wrote a 2024 study testing whether thyroid antibody levels predict progression to hypothyroidism. In chronic lymphocytic thyroiditis, the immune system attacks the thyroid. Antibodies against the enzyme TPO mark that attack. The team asked how antibody concentration relates to the gland's hormone output.
The cross-sectional study began with 144 patients, mean age about 46. After exclusions for out-of-range values, treatment, and other conditions, 85 remained, split between normal and low thyroid function. Antibody levels rose together with TSH, the pituitary signal that climbs as the gland fails. They moved opposite to free thyroxine, the main thyroid hormone. No clear tie to the second hormone, free T3, headlined the results. The authors suggest the pair of measures could flag at-risk people early.
Catalog record
| CREATOR | Mila Vasilj-Mihaljević, Ivan Mihaljević, Sanja Bekić, Željko Zubčić, Ana Vasilj, Danijela Daus-Šebeđak, Ivana Škrlec, Jasminka Talapko |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 22 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |