Hsa_circ_0002346 inhibits proliferation, invasion, and migration of breast cancer cells and promotes apoptosis: A novel potential biomarker for breast cancer
Yixin Zhou, Linyi Wang, Wangjin Xu, Jiaxiang An, Guoming Hu, Feilin Cao, Liming Huang · 2025
Read Hsa_circ_0002346 inhibits proliferation, invasion, and migration of breast cancer cells and promotes apoptosis: A novel potential biomarker for breast cancer by Yixin Zhou, Linyi Wang, Wangjin Xu, Jiaxiang An, Guoming Hu, Feilin Cao, Liming Huang (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12312733.txt.
Description
Yixin Zhou and co-authors study a circular RNA in breast cancer in a paper published in 2024. Circular RNAs are loop-shaped molecules that can steer tumor behavior, but this one's role in breast cancer was unclear. The team measures its levels in cancer cell lines and in tissue from twenty-seven patients.
The molecule runs low in breast cancer, and lower levels track with lymph node spread. Silencing it in cells speeds growth, invasion, and movement while cutting cell death. Proteins tied to a spread-promoting cell transition also shift. The authors propose the molecule as a biomarker and a possible treatment target.
Catalog record
| CREATOR | Yixin Zhou, Linyi Wang, Wangjin Xu, Jiaxiang An, Guoming Hu, Feilin Cao, Liming Huang |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 20 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |